Lab Members

Group Leader

Professor Menna Clatworthy Prof Menna Clatworthy is a Professor of Translational Immunology at the University of Cambridge, a Honorary Consultant Nephrologist at Addenbrooke’s Hospital (Cambridge, UK), Fellow and Director of Studies, Clinical Medicine (Pembroke College, Cambridge), and Associate Faculty at the Wellcome Sanger Institute (Cellular Genetics). She leads the group in understanding how macrophage and B cell activation and IgG antibody effector function is regulated in different tissues, particularly in the kidney and the gut using cellular and molecular immunology, single cells RNA Sequencing and two-photon microscopy.

Assistant to Professor Clatworthy

Ms. Rachel Stojevic Rachel is Professor Clatworthy's assistant.

Lab Manager

Dr. Anais Portet Anais is the Clatworthy lab manager.

Post-doctoral Senior Researcher

John Ferdinand Dr. John Ferdinand is a Senior Research associate in the lab and is interested in using transcriptomic based approaches to understand biology both in steady state and disease and runs the sequencing projects in the lab. John uses both single cell (10x genomics) and bulk sequencing methods to understand the function of the kidney and predict the long term viability of donated kidneys post transplant. John also works on multiple projects for the human cell atlas and is a member of the NIHR blood and transplant unit where he applies sequencing based methods to understand the processes which occur at the molecular level in organ perfusion which is used as a method for both testing and preserving organs prior to transplantation.
Kelvin (Zewen) Tuong Dr. Kelvin Tuong is a computational immunologist interested in single-cell analysis of tissue resident macrophages and B cells in health and disease. He attained his PhD in macrophage cell biology and endocrinology at The University of Queensland (UQ), Australia and went on to a post-doc position with Prof. Ian Frazer (co-inventor of the Gardasil cervical cancer vaccine, UQ Diamantina Institute, Translational Research Institute) where he worked on HPV immunology, cervical cancer and skin cancer. In his time in the Frazer lab, he developed an interest in bioinformatics analyses as a means to tackle and understand immunology problems in health and disease. He is now applying his skillsets in his second post-doc position with Prof. Menna Clatworthy, with a visiting appointment with the Teichmann lab, where he is primarily interested in single-cell analyses of tissue resident macrophages and B cells in kidneys and prostate. He has special interests in scientific illustration and spends his free time coding and illustrating (such as building this website and designing the lab logo).

Research Assistant

Eleanor Gillman Eleanor is a Clatworthy lab research assistant.
Mia Cabantous Mia is a Clatworthy lab research assistant.
Ana Penalver Alonso Ana is a Clatworthy lab research assistant.

Post-doctoral Researchers

Georgina Bowyer Dr. Georgina Bowyer received her bachelor’s degree in Natural Sciences from the University of Cambridge. She then went on to complete a PhD (DPhil) at the University of Oxford in Professor Adrian Hill’s group focusing on human immune responses to malaria and Ebola vaccines. During this project she became interested in the differences between circulating and tissue-resident lymphocytes. Georgie focuses on tissue-resident lymphocyte populations, particularly NK cells. In her spare time, she enjoys running marathons.
Nathan Richoz Dr. Nathan Richoz received his bachelor’s and master’s Degrees from Université Claude Bernard Lyon I where he studied genetics and cell biology and later specialized in immunology. After a year as a flow cytometry technician at the Babraham Institute in Cambridge, he started his PhD split between Dr. Richard Siegel’s lab at the National Institutes of Health (USA) and the Clatworthy Lab in Cambridge. His research, co-funded by the Wellcome Trust and the NIH, focuses on the biology of kidney mononuclear phagocytes and their role in immune complex-mediated nephritis.
Dr. Andrew Guo Andrew is a Clatworthy lab post-doc.
Dr. Willianne Hoepel Willianne is a Clatworthy lab post-doc.
Dr. Tetsuo Hasegawa Tetsuo is a Clatworthy lab post-doc.

PhD students

Kevin Loudon Dr. Kevin Loudon obtained his MBBS in 2008 and has been a renal registrar in the East of England Deanery since 2012. His research interest lies in kidney-resident mononuclear phagocytes and their role in defence against infection and in tissue repair. He spent a year as a clinical research fellow funded by the Addenbrooke’s Charitable Trust / Isaac Newton Trust and has started his PhD with support from a Kidney Research UK Clinical Training Fellowship. He is currently Director of Studies in Medicine at St Edmunds College, Cambridge.
Mary-Ellen Lynall Dr. Mary-Ellen Lynall is a psychiatrist, Medical Research Council Clinical Research Training Fellow and Bye-fellow at Christ’s College, Cambridge. After graduating with First Prize in Natural Sciences (neuroscience) at Cambridge University, she pursued graduate-entry medicine at Oxford, where she was awarded the Gold Medal for highest performance in the clinical school. Following rotations in neurology and neurosurgery as part of the Cambridge Academic Neurosciences Foundation Programme, she entered specialist training in psychiatry and was the Royal College of Psychiatrists Core Trainee of the Year 2017. Mary-Ellen uses human studies and animal models to investigate the mechanisms underlying the associations between stress, inflammation, mood and fatigue. She is co-supervised by Professor Ed Bullmore (Department of Psychiatry) and Dr Menna Clatworthy (Department of Medicine).
Ben Stewart Dr. Benjamin Stewart is a Wellcome Trust funded PhD fellow. His research uses the powerful tools of computational biology and single-cell experimental approaches to understand the landscape and function of tissue resident innate immunity in the kidney.
Aaron Fleming Aaron Fleming completed his undergraduate degree in Natural Sciences at Trinity College Dublin (TCD), specialising in Immunology in his final two years, and graduated with a Gold Medal from the Board of Trinity College. He is funded by the Wellcome Trust as part of the Cambridge Infection, Immunity and Inflammation PhD Programme, looking at the role of innate-like cells in the intestine during health and disease.
David Posner David Posner obtained his BS in Biochemistry from Siena College, a small liberal arts college 3 hours north of New York City. Soon after, he joined Adrian Liston’s team at the Babraham Institute studying regulatory T cells in the context of tissue residency. After a brief intermission at the CRUK Cambridge Institute flow core as a research assistant, he received a CONACYT-Cambridge Trust grant to study the role of resident B cells in the CNS. David is originally from Mexico, he enjoys learning new languages and loves scientific outreach activities.
Zach Fitzpatrick Zach is a NIH Oxford-Cambridge Scholar. He is co-supervised by Prof Menna Clatworthy and Dr Dorian McGavern (NIH).
Dr. Andrew Hotchen Andrew is a PhD student. He is co-supervised by Prof Menna Clatworthy and Prof Andrew McCaskie (University of Cambridge, Division of Trauma and Orthopaedic Surgery).
Daniel Lundgren Daniel is a PhD student. He is co-supervised by Prof Menna Clatworthy and Dr Claudia Kemper (NIH).

Academic Clinical lecturers

Akimichi Inaba Dr. Akimichi Inaba received his bachelor’s degree from Brown University, Rhode Island where studied History of Art and Architecture. Subsequently he completed his medical degree at Guy’s, King’s and St Thomas’ School of Medicine. He completed his PhD during his nephrology training program with Prof Menna Clatworthy in 2019 and is now an academic clinical lecturer investigating the innate function of B lymphocytes. In his spare time, he likes to fly aeroplanes.
Andrew Stewart Dr. Andrew Stewart is a Clinical Lecturer in renal medicine and both a Fellow and the Director of Studies for medicine at Christ’s College. Andy uses a wide variety of techniques including high resolution confocal microscopy, flow cytometry, mass spectroscopy and single cell RNA sequencing to investigate the cellular, micro-vesicle, protein and nucleic acid content of human urine in health and disease. This information allows better understanding of innate and adaptive urothelial defence systems against urinary tract infections, the roles of these processes in renal autoimmune disease and can also be used to non-invasively reveal mechanisms and biomarkers for a variety of other renal pathologies.
Ondrej Dr. Ondrej Suchanek is a NIHR Clinical Lecturer in Renal Medicine at University of Cambridge. He is interested in the maintenance of B cell immune tolerance and mechanisms leading to its breakdown. His current research focuses on identification of tissue-resident B cells across multiple non-lymphoid organs in both mouse and human and examination of their role in shaping local organ immunity. Therapeutic modulation of tissue-resident B cells may have important clinical implications in conditions such as transplant rejection, autoimmunity and cancer.
Dr. James McCaffrey James is a clinical lecturer.
Dr. Simon Ville Simon is a nephrology clincal fellow.

Former members

Rebeccah Mathews (Research Assistant 2010 - 2014, Lab manager 2014 - 2020)

Gordon Fraser (Post-doc 2018-2020)

Ondrej Suchanek (PhD 2020)

Alexandra Riding (PhD 2019)

Laurence Lok (Co-supervised Prof Edwin Chilvers, PhD 2019)

Kirsten Scott (Co-supervised Prof Roger Barker, PhD 2019)

Tom Dennison (Research Assistant 2017 - 2018)

Chenzhi Jing (PhD 2018)

Tomas Castro-Dopico (PhD 2018, post-doc 2018-2020)

Gemma Banham (PhD 2018)

Miriam Berry (PhD 2017)