Lab Members

Group Leader

Professor Menna Clatworthy Prof Menna Clatworthy is a Professor of Translational Immunology at the University of Cambridge, a Honorary Consultant Nephrologist at Addenbrooke’s Hospital (Cambridge, UK), Fellow and Director of Studies, Clinical Medicine (Pembroke College, Cambridge), and Associate Faculty at the Wellcome Sanger Institute (Cellular Genetics). She leads the group in understanding how macrophage and B cell activation and IgG antibody effector function is regulated in different tissues, particularly in the kidney and the gut using cellular and molecular immunology, single cells RNA Sequencing and two-photon microscopy.

Assistant to Professor Clatworthy

Lab Manager

Dr. Yang Cao is the Clatworthy lab manager.

Research Assistant

Eleanor Gillman Eleanor is a Clatworthy lab research assistant.

Post-doctoral Senior Researcher

Kelvin (Zewen) Tuong Dr. Kelvin Tuong is a computational immunologist interested in single-cell analysis of tissue resident macrophages and B cells in health and disease. He attained his PhD in macrophage cell biology and endocrinology at The University of Queensland (UQ), Australia and went on to a post-doc position with Prof. Ian Frazer (co-inventor of the Gardasil cervical cancer vaccine, UQ Diamantina Institute, Translational Research Institute) where he worked on HPV immunology, cervical cancer and skin cancer. In his time in the Frazer lab, he developed an interest in bioinformatics analyses as a means to tackle and understand immunology problems in health and disease. He is now applying his skillsets in his second post-doc position with Prof. Menna Clatworthy, with a visiting appointment with the Teichmann lab, where he is primarily interested in single-cell analyses of tissue resident macrophages and B cells in kidneys and prostate. He has special interests in scientific illustration and spends his free time coding and illustrating (such as building this website and designing the lab logo). Kelvin will be leaving the lab shortly to start his own systems immunology group in Australia, at the Ian Frazer Centre for Children's Immunotherapy Research, UQ, in 2023.

Post-doctoral Researchers

Ben Stewart Dr. Benjamin Stewart is a Wellcome Trust funded PhD fellow. His research uses the powerful tools of computational biology and single-cell experimental approaches to understand the landscape and function of tissue resident innate immunity in the kidney.
Nathan Richoz Dr. Nathan Richoz is an immunologist with an interest in mononuclear phagocytes and advanced imaging techniques. He spent his PhD investigating the role of kidney macrophages in autoimmunity between the National Institutes of Health and the University of Cambridge from which he graduated in 2019. Since then, Nathan has worked as the Imaging Lead for the lab, introducing new imaging techniques involving iterative staining and 2-photon microscopy to support on-going research. In his spare time, he enjoys lifting heavy things.
Dr. Andrew Guo Andrew is a Clatworthy lab post-doc.
Willianne Hoepel Dr. Willianne Hoepel studied at the Utrecht University, the Netherlands, where she obtained her Bachelor Biomedical Sciences and a Master in Infection & Immunology. In 2021 she finished her PhD at the University of Amsterdam in the lab of Dr. Jeroen den Dunnen, investigating the mechanisms behind antibody-dependent inflammation. She continued to work as postdoc in the same lab working on the role of antibody-dependent inflammation in COVID-19. Meanwhile she got awarded a Rubicon grant of the Dutch Research Council, which enabled here to move to Cambridge. Since October 2021, Willianne is a postdoc in the Clatworthy lab investigating kidney tissue immunity.
Tetsuo Hasegawa Dr. Tetsuo Hasegawa is a rheumatologist and received his medical degree at Keio University. He then went on to complete a Ph.D at Keio and Osaka University in Japan focusing on pathological bone destruction in arthritis. He is now funded by HFSP Long-term fellowship to elucidate the pathophysiology of arthritis.

PhD students

Matthew Coates Dr. Matthew Coates is an Ear Nose and Throat surgical trainee and PhD candidate with an interest in nasal immunity. His work uses local anaesthetic nasal associated lymphoid tissue biopsy to investigate human adaptive immune responses to therapeutics and immune challenge. He is co-supervised by Menna Clatworthy and David Jayne.
Kevin Loudon Dr. Kevin Loudon obtained his MBBS in 2008 and has been a renal registrar in the East of England Deanery since 2012. His research interest lies in kidney-resident mononuclear phagocytes and their role in defence against infection and in tissue repair. He spent a year as a clinical research fellow funded by the Addenbrooke’s Charitable Trust / Isaac Newton Trust and has started his PhD with support from a Kidney Research UK Clinical Training Fellowship. He is currently Director of Studies in Medicine at St Edmunds College, Cambridge.
Mary-Ellen Lynall Dr. Mary-Ellen Lynall is a psychiatrist, Medical Research Council Clinical Research Training Fellow and Bye-fellow at Christ’s College, Cambridge. After graduating with First Prize in Natural Sciences (neuroscience) at Cambridge University, she pursued graduate-entry medicine at Oxford, where she was awarded the Gold Medal for highest performance in the clinical school. Following rotations in neurology and neurosurgery as part of the Cambridge Academic Neurosciences Foundation Programme, she entered specialist training in psychiatry and was the Royal College of Psychiatrists Core Trainee of the Year 2017. Mary-Ellen uses human studies and animal models to investigate the mechanisms underlying the associations between stress, inflammation, mood and fatigue. She is co-supervised by Professor Ed Bullmore (Department of Psychiatry) and Dr Menna Clatworthy (Department of Medicine).
Aaron Fleming Aaron Fleming completed his undergraduate degree in Natural Sciences at Trinity College Dublin (TCD), specialising in Immunology in his final two years, and graduated with a Gold Medal from the Board of Trinity College. He is funded by the Wellcome Trust as part of the Cambridge Infection, Immunity and Inflammation PhD Programme, looking at the role of innate-like cells in the intestine during health and disease.
David Posner David Posner is originally from the Bay Area in California and grew up in Morelia, Mexico. David then travelled back to the US for high school and university, where he later obtained his bachelor’s degree in Chemistry and Biochemistry from Siena College, a small liberal arts college 3 hours north of New York City. Soon after, he joined Adrian Liston’s team at the Babraham Institute studying regulatory T cells in the context of tissue residency. After a brief intermission at the CRUK Cambridge Institute flow core as a research assistant, he received a CONACYT-Cambridge Trust grant to study the role of resident B cells in the CNS and adaptive immunity in the dural meninges. David is originally from Mexico; he enjoys learning new languages and loves scientific outreach activities.
Zach Fitzpatrick Zach is a NIH Oxford-Cambridge Scholar. He is co-supervised by Prof Menna Clatworthy and Dr Dorian McGavern (NIH).
Dr. Andrew Hotchen Andrew is a PhD student. He is co-supervised by Prof Menna Clatworthy and Prof Andrew McCaskie (University of Cambridge, Division of Trauma and Orthopaedic Surgery).
Daniel Lundgren Daniel is a PhD student. He is co-supervised by Prof Menna Clatworthy and Dr Claudia Kemper (NIH).

Academic Clinical lecturers

Andrew Stewart Dr. Andrew Stewart is a Clinical Lecturer in renal medicine and both a Fellow and the Director of Studies for medicine at Christ’s College. Andy uses a wide variety of techniques including high resolution confocal microscopy, flow cytometry, mass spectroscopy and single cell RNA sequencing to investigate the cellular, micro-vesicle, protein and nucleic acid content of human urine in health and disease. This information allows better understanding of innate and adaptive urothelial defence systems against urinary tract infections, the roles of these processes in renal autoimmune disease and can also be used to non-invasively reveal mechanisms and biomarkers for a variety of other renal pathologies.
Ondrej Dr. Ondrej Suchanek is a NIHR Clinical Lecturer in Renal Medicine at University of Cambridge. He is interested in the maintenance of B cell immune tolerance and mechanisms leading to its breakdown. His current research focuses on identification of tissue-resident B cells across multiple non-lymphoid organs in both mouse and human and examination of their role in shaping local organ immunity. Therapeutic modulation of tissue-resident B cells may have important clinical implications in conditions such as transplant rejection, autoimmunity and cancer.
Dr. James McCaffrey James is a clinical lecturer.

Former members

Georgina Bowyer (Post-doc 2019-2022)

Ana Penalver Alonso (Research Assistant 2020-2022)

Mia Cabantous (Research Assistant 2020-2022)

John Ferdinand (Post-doc 2013-2020, Senior Post-doc 2020-2022)

Anais Portet (Research Assistant 2019-2020, Lab manager 2020 - 2022)

Akimichi Inaba (PhD, Academic Clinical Lecturer 2020 - 2022)

Simon Ville (Nephrology Clincal Fellow, 2020-2021)

Rebeccah Mathews (Research Assistant 2010 - 2014, Lab manager 2014 - 2020)

Gordon Fraser (Post-doc 2018-2020)

Ondrej Suchanek (PhD 2020)

Alexandra Riding (PhD 2019)

Laurence Lok (Co-supervised Prof Edwin Chilvers, PhD 2019)

Kirsten Scott (Co-supervised Prof Roger Barker, PhD 2019)

Tom Dennison (Research Assistant 2017 - 2018)

Chenzhi Jing (PhD 2018)

Tomas Castro-Dopico (PhD 2018, post-doc 2018-2020)

Gemma Banham (PhD 2018)

Miriam Berry (PhD 2017)